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CV Safety Outcomes
CARMELINA CV events graph full text
- CARMELINA CV events graph showing the demonstrated time to first occurrence of CV death, nonfatal MI or nonfatal stroke (primary composite endpoint) for Trajenta® (n=3,494) and placebo (n=3,485).
- Y-axis shows the patients with event from 0 to 30%. Years from 0.0 to 3.5 is on the x-axis.
- The hazard ratio was 1.02 (95% confidence interval: 0.89 to 1.17), p<0.0002 for non-inferiority. Subjects with events was 12.4% (n=434) for Trajenta® vs. 12.1% (n=420) for placebo.
- Patients at risk for placebo: 3,485 at Year 0.0, 3,353 at Year 0.5, 3,243 at Year 1.0, 2,625 at Year 1.5, 1,931 at Year 2.0, 1,285 at Year 2.5, 758 at Year 3.0 and 251 at Year 3.5.
- Patients at risk for Trajenta®: 3,494 at Year 0.0, 3,373 at Year 0.5, 3,254 at Year 1.0, 2,634 at Year 1.5, 1,972 at Year 2.0, 1,306 at Year 2.5, 778 at Year 3.0 and 269 at Year 3.5.
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