Elementary Lesions
Elementary Lesions
Simple Centrilobular Micronodulation
Simple Centrilobular Micronodulations are primarily associated with small airways diseases
- Bronchiolar inflammation
- Hypersensitivity pneumonitis, respiratory bronchiolitis, histiocytosis, asthma, allergic bronchopulmonary aspergillosis, follicular bronchiolitis (connective tissues), pneumoconiosis
- Lepidic adenocarcinoma
- Infectious bronchiolitis
- Tuberculosis, atypical mycobacteria, bronchopneumonia
This Lesion can also be found
- In angiocentric conditions: pulmonary oedema, vasculitis, talcosis, pulmonary haemorrhage, haemosiderosis, metastatic calcifications, pulmonary arterial hypertension, metastases
- In perilymphatic conditions, the centrilobular nodules are rarely isolated
Simple Centrilobular Micronodulation
Poorly defined and low attenuation micronodules within the upper lobes in an active
smoker.
References
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Collège des Enseignants de Pneumologie. Item 206 (ex item 120). Pneumopathies interstitielles diffuses. 2013
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Cottin V, et al. French practical guidelines for the diagnosis and management of idiopathic pulmonary fibrosis - 2017 update. Full-length version. Rev Mal Respir 2017;34:900-68
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Brauner M, et al. Imagerie des pneumopathies diffuses. Press Med 2010 39: 73-84
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Raghu G, et al. Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med 2018;198:e44-e68