HIGH UNMET NEED OF GPP | Generalized Pustular Psoriasis (GPP) Egypt

THERE IS A LACK OF APPROVED GPP-SPECIFIC THERAPIES¹

Current treatment options lack the efficacy required to adequately manage Generalized Pustular Psoriasis (GPP) flares. Even with treatment, symptoms of GPP flares can persist, and patients continue to suffer.¹

There is clearly a need for treatments that resolve GPP flares more
quickly, and also for treatments that are approved specifically for
GPP.”

GPP-SPECIFIC GUIDELINES ARE LACKING¹

The standard of care for GPP varies across geographies. There is a need for international, evidence based guidelines for the management of GPP flares.¹

Due to the rarity of disease, the guideline recommendations to date
are based on very low-quality data.”¹

THERE IS A NEED FOR THERAPIES THAT

Provide sustained disease control¹

Rapidly and effectively resolve GPP ﬂares

Rapidly and effectively resolve GPP flares¹

Have an acceptable safety profile¹

Replace current treatment options that have limited efﬁcacy

Replace current treatment options that have limited efficacy³

REFERENCES

Strober B, Kotowsky N, Medeiros R, et al. Unmet Medical Needs in the Treatment and Management of Generalized Pustular Psoriasis Flares: Evidence from a Survey of Corrona Registry Dermatologists. Dermatol Ther (Heidelb). 2021;11(2):529-541
Krueger J. Puig L. Thaci D - Treatment Options and Goals for Patients with Generalized Pustular Psoriasis. American Journal of ClinicalDermatology (2022) Suppl 1):S51–S64) 23
Johnston A, Xing X, Wolterink L, et al. IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. J Allergy Clin Immunol. 2017;140(1):109-120

THE HIGH UNMET NEED OF GPP1

THERE IS A LACK OF APPROVED GPP-SPECIFIC THERAPIES1

GPP-SPECIFIC GUIDELINES ARE LACKING1

THERE IS A NEED FOR THERAPIES THAT

Provide sustained disease control1

Rapidly and effectively resolve GPP flares1

Have an acceptable safety profile1

Replace current treatment options that have limited efficacy3