^aUse of Diuretics:–Consider transition to Loop Diuretic if eGFR is between 30 to 45 ml/min/1.73 m²–If eGFR <30 ml/min/1.73 m² use Loop Diuretic,
^bBB should be used as guideline directed medical therapy in respective indications or considered in several other conditions,  
^cControlled below 140/90  mmHg,  
^dWhen SBP is ≥140 mmHg or DBP is ≥90 mmHg provided that:–maximum recommended and tolerated doses of a three-drug combination comprising 
a RAS blocker (either an ACEi or an ARB), a CCB and a Thiazide/Thiazide-like diuretic were used–adequate BP control has been confirmed by ABPM or by HBPM if ABPM is not feasible–various causes of pseudo-resistant hypertension (especially poor medication adherence) and secondary hypertension have been excluded