STEMI treatment guidelines

STEMI guidelines state that acute myocardial ischaemia (<12 h) should be treated with reperfusion therapy1,2. Guidelines from the ACC/AHA1 and ESC2 agree that:

  1. Primary PCI (PPCI) is the gold-standard of reperfusion treatment for STEMI if delivered ≤120 minutes of diagnosis.

  2. Where this is not possible, fibrinolysis should be performed with a fibrin-specific agent (tenecteplase, alteplase or reteplase) as soon as possible within 10 min from STEMI diagnosis, preferably pre-hospital, alongside adjunctive antiplatelet and anticoagulant therapies, and patients should be transferred to a PCI-capable centre for subsequent therapy.

 

STEMI treatment guidelines

ACC/AHA, American College of Cardiology/American Heart Association
ESC, European Society of Cardiology
PPCI, primary percutaneous coronary intervention

References: 
  1. O’Gara PT et al. 2013 ACCF/AHA Guideline for the management of ST-Elevation myocardial infarction: A report of the American college of cardiology foundation/American Heart Association task force on practice guidelines. Circulation 2013;127:e362-e425.

  2. Ibanez B et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2018;39(2):119-177.