The delivered dose is 2.5 microgram tiotropium and 2.5 microgram olodaterol per puff. The recommended dose is two puffs (5
microgram tiotropium and 5 microgram olodaterol) from the SPIOLTO® RESPIMAT® inhaler once daily, at the same time of the
day.¹

SPIOLTO® RESPIMAT® is NOT indicated for the treatment of acute episodes of bronchospasm, i.e. as rescue therapy.¹

REMEMBER TO TELL YOUR PATIENTS: 1 DOSE = 2 PUFFS ONCE DAILY¹

Do not use more than 2 puffs every 24 hours.

Prepare for use¹

1. Remove clear base

Keep the cap closed.
Press the safety catch while pulling off the clear base with the other hand.

2. Insert cartridge

Insert the narrow end of the cartridge into the inhaler.
Place the inhaler on a firm surface and push down firmly until it snaps into place.

3. Replace clear base

Put the clear base back into place until it clicks.

4. Turn

Keep the cap closed.
Turn the clear base in the direction of the arrows on the label until it clicks (half a turn).

5. Open

Open the cap until it snaps fully open.

6. Press

Point the inhaler towards the ground.
Press the dose-release button.
Close the cap.
Repeat steps 4-6 until a cloud is visible.
After a cloud is visible, repeat steps 4-6 three more times.

The inhaler is now ready to use. These steps will not affect the number of doses available. After preparation, the inhaler will be able to deliver 60 puffs (30 doses).

Daily use¹

1. TURN

Keep the cap closed.
TURN the clear base in the direction of the arrows on the label until it clicks (half a turn)

2. OPEN

OPEN the cap until it snaps fully

3. PRESS

Breathe out slowly and fully.
Close the lips around the mouthpiece without covering the air vents.
While taking a slow, deep breath through the mouth, PRESS the dose-release button and continue to breathe in.
Hold the breath for 10 seconds or for as long as comfortable.
Repeat TURN, OPEN, PRESS for a total of 2 puffs.

When to get a new SPIOLTO® RESPIMAT®

Your SPIOLTO® RESPIMAT® inhaler contains 60 puffs (30 doses) if used as indicated (two puffs/Once daily).
The dose indicator shows approximately how much medication is left.
When the dose indicator enters the red area of the scale you need to get a new prescription; there is approximately medication for 7 days left (14 puffs).
Once the dose indicator reaches the end of the red scale, your SPIOLTO® RESPIMAT® locks automatically – no more doses can be released. At this point, the clear base cannot be turned any further.
At the latest, three months after use the SPIOLTO® RESPIMAT® inhaler should be discarded even if not all medication has been used.

Reference:

SPIOLTO® RESPIMAT® Summary of Product Characteristics.

SPIOLTO® RESPIMAT®

Dosing and administration