Dosing and administration

The recommended dose of TRAJENTA® is 5 mg once daily.1

  • TRAJENTA® can be used as an adjunct to diet and exercise as monotherapy or in combination with metformin, sulfonylurea, insulin or PPARγ agonists (such as thiazolidinediones) to improve glycemic control.

  • TRAJENTA® can be taken with or without food.

  • When TRAJENTA® is used in combination with an insulin secretagogue (eg, sulfonylurea) or insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.

 

0% inappropriate dose risk in patients with renal failure.2

  • Dose adjustment is not required in patients with renal impairment or with hepatic impairment.

Footnote:

  • PPARγ, Peroxisome proliferator-activated receptor γ.

References:

  1. TRAJENTA® approved package insert. Updated in May 2020. 

  2.  Abigail Tebboth et al, Clinical Therapeutics, 38, 8, August 2016, 1825-1832.

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