JARDIANCE® (Empagliflozin)
The content on this website is in relation to adult patients
Dose & Administration
JARDIANCE® (empagliflozin) is simple to initiate at 10 mg dosing across all indications.1
Quick links
10mg OD down to eGFR 20mL/min/1.73m2
Swallowed whole with water & taken with or without food
No titration
No upper age limit for initiation*
Indications
Heart failure
JARDIANCE® is indicated in adults for the treatment of symptomatic chronic heart failure.1
Type 2 diabetes
JARDIANCE® is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise
- as monotherapy when metformin is considered inappropriate due to intolerance
- in addition to other medicinal products for the treatment of diabetes 1
According to the 5.1 section of the SmPC, both improvement of glycaemic control and reduction of cardiovascular morbidity and mortality are an integral part of the treatment of type 2 diabetes.1
Chronic kidney disease
JARDIANCE® is indicated in adults for the treatment of chronic kidney disease.1
Indications
Heart failure
JARDIANCE® is indicated in adults for the treatment of symptomatic chronic heart failure.1
Type 2 diabetes
JARDIANCE® is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise
- as monotherapy when metformin is considered inappropriate due to intolerance
- in addition to other medicinal products for the treatment of diabetes 1
According to the 5.1 section of the SmPC, both improvement of glycaemic control and reduction of cardiovascular morbidity and mortality are an integral part of the treatment of type 2 diabetes.1
Chronic kidney disease
JARDIANCE® is indicated in adults for the treatment of chronic kidney disease.1
Empagliflozin is not recommended in severe hepatic impairment, breastfeeding, type 1 diabetes, and is contraindicated in patients with hypersensitivity to the active ingredient or any of its excipients. Empagliflozin should be avoided in pregnancy.
* Use with caution in patients aged ≥75 years and in those for whom a drop in blood pressure could pose a risk.
Learn more
Digital patient booklet
JARDIANCE Initiation & Management guide for T2D, CHF and CKD
Abbreviations
CHF: chronic heart failure; CKD: chronic kidney failure; eGFR: estimated glomerular filtration rate; LVEF: left ventricular ejection fraction; SoC: standard of care; T2D: type 2 diabetes
References
- JARDIANCE® (empagliflozin) Summary of Product Characteristics (SmPC). Available at: http://www.medicines.org.uk/emc/medicine/28973.
PC-GB-109670
February 2024