SPIRIVA® Respimat®
Tiotropium (for COPD)
Product Overview
SPIRIVA® Respimat® (tiotropium) is indicated as a maintenance bronchodilator treatment to relieve symptoms of adult patients with chronic obstructive pulmonary disease (COPD).1
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Mechanism of Action
SPIRIVA® Respimat® is an inhalation solution containing tiotropium, a long-acting muscarinic receptor antagonist (LAMA), which is delivered via the Respimat® inhaler device.1 Tiotropium bromide is a long-acting, specific antagonist at muscarinic receptors.1
In the airways, tiotropium bromide competitively and reversibly binds to the M3 receptors in the bronchial smooth muscle, antagonising the cholinergic (bronchoconstrictive) effects of acetylcholine, resulting in bronchial smooth muscle relaxation.1
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SPIOLTO® RESPIMAT® is indicated as a maintenance bronchodilator treatment to relieve symptoms in adult patients with COPD.3
Product Key Facts
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Abbreviations
LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist.
References
1.
SPIRIVA® Respimat® Summary of Product Characteristics.
2.
Global Initiative for Chronic Obstructive Lung Disease, Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease; updated 2023. Available at: https://goldcopd.org/.
3.
SPIOLTO® RESPIMAT® Summary of Product Characteristics.
PC-GB-102134 V2
August 2023