Male Doctor Standing With Female Patient Who Has Chronic Kidney Disease (CKD)

It takes 2 tests to get the full picture about chronic kidney disease (CKD)

Your patients with type 2 diabetes or hypertension may have CKD without even knowing it, and eGFR testing only tells half the story.

Breaking down CKD by the numbers

CKD is a debilitating condition that often goes undiagnosed until late stages.

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adults in the U.S. have CKD

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people with CKD are not aware of their condition

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Black Americans are 3 times as likely to have kidney failure compared to white Americans

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Latin Americans are 1.3 times as likely to have kidney failure compared to white Americans

It Takes 2 – Remixing the ‘80’s Hit for 
Kidney Health Awareness

Rob Base may have said it best: “It takes two to make a thing go right” – and that applies to your patients’ kidney 
health too. The musical artist rewrites his 1980’s hit song to bring attention to the importance of early diagnosis 
and treatment of CKD, and how It Takes 2 tests – eGFR and uACR – to detect kidney disease and help reduce the 
potential for serious complications.

It takes two to make a thing go right. It takes two to make it outta sight. I wanna talk right now. I’m Rob Base and I’m back to throw down. Now, I’m internationally known. Rocking wisdom from the microphone. These health conditions. Let’s put attention to this mission. You gotta just listen. People with no symptoms to show. Could have kidney disease – and not know. Follow the advice, don’t neglect it. Gotta make the effort to detect it ‘cause. It takes two to make a thing go right. It takes two to make it outta sight. It takes two to make a thing go right. It takes two to make it outta sight. I got a message that I wanna to share. Stop a minute, listen up, you gotta care. No matter what you gotta do what’s best. It all starts with an extra test, yea. If you think I’m wrong, you’re a doubter. Reach for that test ‘cause knowledge is power. Early detection is important. Gotta be smart let’s go and make sure everything’s all right. Cause it takes two to make it out of sight, come on. It takes two to make a thing go right. It takes two to make it outta sight.

Changing the Tune of Kidney Disease 
Diagnosis

Adults with type 2 diabetes and hypertension are more likely to develop CKD, but the condition is often asymptomatic 
in its early stages. If your patient is living with either of these conditions, using two tests – eGFR and UACR – can 
help reveal the full picture of kidney health. Head behind the scenes with Rob Base, Dr. Charles Vega, a primary 
care physician, and Thelma, an advocate living with CKD, to learn about the importance of testing and early 
diagnosis.

Dr. Charles Vega: In the United States, there are two major risk factors for chronic kidney disease, and those are diabetes and hypertension. And those cases account for 75% of folks with chronic kidney disease in the United States. Still, about 90% of folks with chronic kidney disease in the U.S. don’t know they have it, so it really is the silent killer. Thelma: Once I found out, I was devastated. I went to about three nephrologists before I actually settled in on “this is my disease; this is my diagnosis. I have to live with it.”Dr. Charles Vega: Certainly, if you have diabetes and hypertension, you should have an annual check of your blood and urine. This is something you want to bring up to your clinician. And be frank, say, “I’m worried about kidney disease. Could you run a blood test? Could you run a urine test?” You know, Thelma knows those tests really, really well. And as well as any doctor I know.Thelma: I think that we have to be willing to advocate for ourselves, not be afraid to talk to your doctors. So many of us go to the doctors and we’re afraid to talk. We’re afraid to advocate for ourselves. You have to understand this is helping to save your life. Well, it does take two – you and your doctor – because it is a partnership. You know, your doctor is responsible to take care of you and you’re responsible to communicate to your doctor what’s actually going on with you.Rob Base: By spreading awareness through music is a great thing because you get to reach people that you wouldn’t normally reach. When I talk to a lot of people, I tell them what happened to my best friend, DJ E-Z Rock, you know, that he passed away from diabetes. So, you know, it’s just getting the message out there to everybody.Dr. Charles Vega: I think it’s something that resonates with a lot of folks who happen to be at risk for chronic kidney disease, maybe because they’re a little older now.Thelma: The theme is it takes you as a patient with your doctor, the doctor with the patient, it takes two to make it all right. And make it out of sight and dynamite with you, right?

Even though I'd been treated for type 2 diabetes for 10 years, I was already at late-stage kidney disease when I was diagnosed. I wish I knew about the connection between hypertension, type 2 diabetes and kidney disease sooner, and encourage others at-risk for this disease, like I was, to get tested.
Patrick
Patrick
Living with CKD

One test isn’t enough

When combined with eGFR, UACR allows healthcare professionals to stage and stratify the risk of CKD progression.

Using both urine albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) tests can help to completely screen for CKD in at-risk patients.

Prognosis of CKD by GFR and Albuminuria categories: KDIGO 2012
Female  Doctor Standing With Male Patient Who Has Chronic Kidney Disease (CKD)

EARLY TESTING CAN MEAN EARLY TREATMENT

  • Less than 20% of patients at risk for CKD between 2013 and 2019 received complete testing (defined as both eGFR and UACR) for CKD

  • Only 10.5% of people with hypertension had complete testing

  • SGLT2 inhibitors with documented kidney or cardiovascular benefit, ACE inhibitors, and ARBs are some of the recommended therapies for CKD

Meet the healthcare professionals 
behind It Takes 2

As valued members of the healthcare community, these HCPs understand the interconnected nature of type 2 
diabetes, hypertension and CKD and recognize the critical need for comprehensive testing to help delay CKD 
progression.

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Dr. Eugene Wright, M.D.

With more than 40 years of clinical experience as a private practitioner, academic clinician and educator, medical administrator, and volunteer physician, Dr. Eugene Wright, M.D., is a wealth of knowledge and experience for his patients. He currently works as Medical Director for Performance Improvement at the South Piedmont Health Education Center and served on several advisory and editorial boards, including Clinical Diabetes, Diabetes Technology and Therapeutics. He has published several articles on diabetes diagnoses, treatment, and management and presented new treatments and diabetes technology around the world. 

family medicine specialist sitting in chair smiling

Dr. Charles Vega, M.D.

Charles Vega, M.D., is a family medicine specialist and Director of UC Irvine’s Program in Medical Education for the Latino Community. Throughout his 27-year residency at UCI’s Family Health Center, the largest safety-net clinic in Orange County, he’s used his extensive knowledge and experience to shape the next generation of medical students and residents. Dr. Vega has won numerous awards in recognition of his work in the development of training programs that provide quality, compassionate care to underserved populations.