When evaluating a series of HRCT scans, it is important to take note of both the dominant pattern or patterns and their distribution within the lungs. Honeycombing, reticulation, traction bronchiectasis, and volume loss are hallmark features of fibrosis,5,8 but scans from patients with fibrotic lung disease will often have signs of opacities such as ground glass opacity. The pattern of distribution will also give clues to the underlying disorder, as reviewed in the following section.

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Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

Reference

5. Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med. 2011;183:788-824.

8. Lynch DA, Godwin JD, Safrin S, et al. High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis. Am J Respir Crit Care Med. 2005;172:488-493.